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Squamous Cell Carcinoma Basal Cell Carcinoma Carcinoma Lentigo, Solar Malignant Melanin Melanocytes Melanoma Nevus A malignant neoplasm that is derived from stratified squamous epithelium, but that may also occur in sites where glandular or columnar epithelium is normally present; variable amounts of keratin are formed, in relation to the degree of differentiation, and, if the keratin is not on the surface, it accumulates in the neoplasm as a ''keratin pearl''; in instances in which the cells are well differentiated, intercellular bridges may be observed between adjacent cells.